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Anesth Analg 2007;104:308-311
© 2007 International Anesthesia Research Society
doi: 10.1213/01.ane.0000252927.10415.ec

AMBULATORY ANESTHESIA

Acupuncture of LI-4 in Anesthetized Healthy Humans Decreases Cerebral Blood Flow in the Putamen Measured with Positron Emission Tomography

Lise Schlünzen, MD*, Manouchehr S. Vafaee, MSc, PhD{dagger}, and Georg E. Cold, MD, DMSc*

From the *Department of Neuroanaesthesiology; and {dagger}PET Centre, Aarhus University Hospital, Aarhus, Denmark.

Address correspondence and reprint requests to Lise Schlünzen, MD, Department of Neuroanesthesiology, Aarhus University Hospital, Noerrebrogade 44, 8000 Aarhus C, Denmark. Address e-mail to lise.schlunzen{at}dadlnet.dk.

To minimize the influence of exogenous factors, 13 volunteers were anesthetized with sevoflurane 1 MAC while exposed to manual acupuncture stimulation of LI-4 (Group 1, n = 7) or a placebo point in the space between the third and fourth metacarpals (Group II, n = 6). During anesthesia (baseline) and anesthesia + acupuncture, one H215O scan was performed, respectively. Group I demonstrated a significant decrease in regional cerebral blood flow in the right medial frontal gyrus (20%) and in the left putamen (17%). In Group II regional cerebral blood flow was decreased in the right medial frontal gyrus (22%); in the putamen no significant changes were observed. These data suggest that needle penetration of the skin affects the medial frontal gyrus, whereas acupuncture of LI-4 influences the putamen.




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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2007 by the International Anesthesia Research Society.