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Anesth Analg 1977; 56:271-275
© 1977 International Anesthesia Research Society
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Fade of Neurally Evoked Compound Electromyogram During Neuromuscular Block by d-Tubocurarine

CHINGMUH LEE, MD*, and RONALD L. KATZ, MD{dagger}

*Associate Professor, Department of Anesthesiology (UCLA), Harbor General Hospital Campus, Torrance, California {dagger}Professor and Chairman, Department of Anesthesiology, UCLA School of Medicine, Los Angeles, California 90024.

Abstract

Trains of neurally evoked compound electro-myographic responses of the thenar muscles were studied in 20 patients anesthetized with enflurane and N2O and paralyzed with d-tubocurarine. Fade was correlated with stimulus frequency (0.1 to 50 Hz) and degree of neuromuscular block. The lowest response in a train occurred on the 4th and the 6th-to-8th responses when the train was elicited at 2 Hz and 50 Hz, respectively. Fade was more observable with deeper block and could best be demonstrated by 5 Hz stimuli. With 50 Hz stimuli, a concomitant facilitation, observable from the beginning of the train, partially compensated for the fade.







Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1977 by the International Anesthesia Research Society.