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*Assistant Professor.
Resident in Anesthesiology.
Department of Anesthesiology, University of Kansas Medical Center, Kansas City, Kansas 66103.
Abstract
Two preoperatively unsuspected and one known hypothyroid patients underwent elective surgery with general anesthesia. All demonstrated unusual sensitivity to anesthetic agents. As suggested by a history of thyroid abnormalities, high serum cholesterol, and exaggerated response to anesthetic agents, the authors were led to suspect hypothyroidism, which was confirmed postoperatively by low serum thyroxine levels.
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