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Anesth Analg 1977; 56:348-351
© 1977 International Anesthesia Research Society
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Physostigmine Reversal of Diazepam-Induced Depression

G. FOSTER LARSON, MD*, BARBARA J. HURLBERT, MD{dagger}, and DANIEL W. WINGARD, MD{ddagger}

*Assistant Professor, Department of Anesthesiology, University of Nebraska Medical Center, Omaha, Nebraska 68105. {dagger}Assistant Professor, Department of Anesthesiology, University of Nebraska Medical Center, Omaha, Nebraska 68105. {ddagger}Professor and Chairman, Department of Anesthesiology, University of Nebraska Medical Center, Omaha, Nebraska 68105.

Abstract

Diazepam is a valuable and widely-used adjunct to many inpatient and outpatient diagnostic and therapeutic procedures. However, the occasional and often unexpected delirium or coma induced by even modest doses of diazepam can be life threatening. Four cases are reported which demonstrate the prompt and effective reversal of diazepam-induced delirium and coma by the administration of physostigmine.




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[Abstract] [PDF]


Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1977 by the International Anesthesia Research Society.