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Anesth Analg 1977; 56:489-492
© 1977 International Anesthesia Research Society
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Intramuscular Lo razepa m Versus Pen tobarbi tal Premedica tion

A Comparison of Patient Sedation, Anxiolysis, and Recall

MONICA I. ALENIEWSKI, MD*, BENIGNA J. BULAS, MD{dagger}, LEONAR MADERAZO, MD{ddagger}, CORAZON MENDOZA, MD§, ROBERT K. STOELTING, MD*, and FRANK J. TORNETTA, PhD, MD*

*Chief of Anesthesia Service, Veterans Administration Hospital, East Orange, New Jersey, 07019; Associate Professor of Anesthesiology, College of Medicine and Dentistry of New Jersey, Newark, New Jersey. {dagger}Assistant Chief of Anesthesiology, VA Hospital; Assistant Professor of Anesthesiology, College of Medicine and Dentistry. {ddagger}Staff Anesthesiologist, VA Hospital; Instructor, Department of Anesthesia, College of Medicine and Dentistry. §Staff Anesthesiologist, VA Hospital; Instructor, Department of Anesthesia, College of Medicine and Dentistry.

Abstract

In a double-blind, controlled study in 40 veterans, IM lorazepam was significantly superior to IM pentobarbital as a preoperative sedative and in ability to suppress the memory of events of the operative day. A trend was noted (not statistically significant in this small series) toward greater patient acceptance of lorazepam. No important adverse effects or changes in vital signs occurred with either agent.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1977 by the International Anesthesia Research Society.