JOURNAL HOME CME HOME THIS MONTH PAST ISSUES ETOC COLLECTIONS
AUTHORS REVIEWERS EDITORIAL BOARD FEEDBACK RSS HELP
A&A International Anesthesia Research Society
QUICK SEARCH:   [advanced]


     

Anesth Analg 1977; 56:493-495
© 1977 International Anesthesia Research Society
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a colleague
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by STOELTING, R. K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by STOELTING, R. K.

Comparison of Gallamine and Atropine as Pretreatment Before Anesthetic Induction and Succinylcholine Administration

ROBERT K. STOELTING, MD

Professor of Anesthesia/Pharmacology, Indiana University School of Medicine, Indianapolis, Indiana 46202.

Abstract

Heart-rate changes following pretreatment with IV gallamine 0.3 mg/kg (40 patients) or atropine 0.006 mg/kg (40 patients) and the incidence of heart-rate slowing and/or junctional rhythm after thiamylal anesthetic induction and 2 injections of succinylcholine (SCh) were determined in adult patients. Awake heart rate increased 13 and 16 bpm (p<0.05) 1 and 3 minutes after gallamine. In contrast, heart rate was unchanged 1 minute after atropine and then was increased about 10 bpm (p<0.05) 3 minutes later. Heart-rate slowing (greater than 15% as compared with the rate immediately before SCh) and junctional rhythm occurred in 1 patient from each group following the 1st SCh dose. Heart-rate slowing after the 2nd SCh injection occurred in 1 patient pretreated with gallamine and in 14 patients pretreated with atropine. Junctional rhythm did not occur in any patient after the 2nd SCh dose. The authors conclude that IV gallamine is more effective than atropine in preventing heart-rate slowing after repeated SCh administration.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1977 by the International Anesthesia Research Society.