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Hyperglycemic Hyperosmolar Nonketotic Coma Following Diazoxide, Anesthesia and Operation

BAEKHYO SHIN, MD^*, and SAMUEL I. JOSEPH, PhD, MD

*Assistant Professor. Professor. Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland 21201.

Abstract

Unsuspected hyperglycemia caused prolonged postanesthetic coma in a nondiabetic patient treated with IV diazoxide and furosemide. The combined effect of these drugs with general anesthesia and surgical stress was postulated as the cause of the hyperglycemia. Blood glucose should be measured during and after general anesthesia in patients who are potential candidates for hyperglycemic hyperosmolar nonketotic coma.

This article has been cited by other articles:

				L. Lang-Lazdunski, C. Heurteaux, and M. Lazdunski Diazoxide for cerebral protection during deep hypothermic circulatory arrest: is it really safe? Ann. Thorac. Surg., August 1, 2002; 74(2): 632 - 632. [Full Text] [PDF]

Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999