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Effect of Halothane on Systolic Time Intervals

JAN D. HASBROUCK, MD^*, and CATHERINE C. COLEMAN, BS

*Professor, Department of Anesthesiology, Southern Illinois University School of Medicine, Springfield, Illinois 62708. Third Year Medical Student, University of Kentucky, Lexington, Kentucky 40506.

Abstract

By simultaneous rapid-strip recordings of the electrocardiogram, phonocardiogram, and carotid pulse wave, systolic time intervals (STI) can be calculated and used to assess cardiac activity during general anesthesia. The principal advantage of this methodology over more conventional technics of determining anesthetic effects on the heart is that it is noninvasive.

One anesthetic agent, halothane, was chosen to illustrate the usefulness of the technic. Results obtained by using STI supported the well-documented effect of myocardial depression produced by halothane. Because the equipment and technic are relatively simple, this procedure has definite clinical applications.

Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999