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Anesth Analg 1977; 56:589-593
© 1977 International Anesthesia Research Society
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Fatal Hepatic Necrosis After Halothane Anesthesia in a Boy with Juvenile Rheumatoid Arthritis

A Case Report

ROBERT L. CAMPBELL, DDS*, ERNEST W. SMALL, DDS, MS{dagger}, HENRY R. LESESNE, MD{ddagger}, KENNETH J. LEVIN, MD§, and WARREN H. MOORE, MD||

*Clinical Assistant Professor of Oral Surgery; Resident in Anesthesiology, North Carolina Memorial Hospital. {dagger}Professor and Chairman, Department of Oral Surgery. University of North Carolina School of Medicine, Chapel Hill, North Carolina 27514. {ddagger}Associate Professor, Department of Medicine. University of North Carolina School of Medicine, Chapel Hill, North Carolina 27514. §Associate Professor and Vice Chairman, Department of Anesthesiology. University of North Carolina School of Medicine, Chapel Hill, North Carolina 27514. ||Medical Intern, The Medical College of South Carolina, Charleston, South Carolina. University of North Carolina School of Medicine, Chapel Hill, North Carolina 27514. University of North Carolina School of Medicine, Chapel Hill, North Carolina 27514.

Abstract

Hepatitis from halothane is usually diagnosed by excluding other possible causes. Whether preexisting hepatic damage, which can occur in certain autoimmune disorders, contraindicates the use of halothane has yet to be proven. The case of a 14-year-old boy with early-onset juvenile rheumatoid arthritis who developed fatal hepatic necrosis 13 days after halothane anesthesia is presented.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1977 by the International Anesthesia Research Society.