JOURNAL HOME CME HOME THIS MONTH PAST ISSUES ETOC COLLECTIONS AUTHORS REVIEWERS EDITORIAL BOARD FEEDBACK RSS HELP
		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by STOELTING, R. K. Search for Related Content PubMed PubMed Citation Articles by STOELTING, R. K.

Circulatory Response to Laryngoscopy and Tracheal Intubation With or Without Prior Oropharyngeal Viscous Lidocaine

Professor and Chairman, Department of Anesthesia, Indiana University School of Medicine, Indianapolis, Indiana 46202.

Abstract

Oropharyngeal topical anesthesia with viscous lidocaine (25 ml of 2% as a "mouthwash and gargle" 10 min before laryngoscopy) attenuated the pressor but not heart rate (HR) response during laryngoscopy and tracheal intubation. Compared with control patients, mean arterial pressure (MAP) increased less in response to tracheal intubation (23 ± 5 torr versus 39 ± 4 torr, p <0.05) and returned toward awake levels sooner in patients receiving viscous lidocaine. MAP increased more than 40 torr in response to intubation in 6/20 patients treated with viscous lidocaine, while 12/20 control patients manifested this degree of blood pressure elevation. HR increased about 20 bpm (p< 0.05) with or without viscous lidocaine. Arterial lidocaine concentrations were less than 0.5 µg/ml after oropharyngeal anesthesia. Prior topical anesthesia of the oropharynx with viscous lidocaine should be considered when pressor responses during tracheal intubation would be particularly likely or hazardous.

This article has been cited by other articles:

				W. Oczenski, H. Krenn, A. A. Dahaba, M. Binder, I. El-Schahawi-Kienzl, H. Jellinek, S. Schwarz, and R. D. Fitzgerald Hemodynamic and Catecholamine Stress Responses to Insertion of the Combitube(R), Laryngeal Mask Airway or Tracheal Intubation Anesth. Analg., June 1, 1999; 88(6): 1389 - 1389. [Abstract] [Full Text] [PDF]

Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999