JOURNAL HOME CME HOME THIS MONTH PAST ISSUES ETOC COLLECTIONS
AUTHORS REVIEWERS EDITORIAL BOARD FEEDBACK RSS HELP
A&A International Anesthesia Research Society
QUICK SEARCH:   [advanced]


     

Anesth Analg 1977; 56:808-812
© 1977 International Anesthesia Research Society
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a colleague
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by FRAGEN, R. J.
Right arrow Articles by CALDWELL, N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by FRAGEN, R. J.
Right arrow Articles by CALDWELL, N.

Acute Intravenous Premedication with Nalbuphine

ROBERT J. FRAGEN, MD*, and NANCY CALDWELL, CRNA{dagger}

*Associate Professor of Clinical Anesthesia. {dagger}Research Assistant in Anesthesia. Department of Anesthesia, Northwestern University Medical School and Northwestern Memorial Hospital, Chicago, Illinois 60611.

Abstract

In a randomized, double blind study of 75 adult surgical patients, nalbuphine (0.1 mg/kg), morphine (0.1 mg/kg), or a placebo were administered intravenously as premedication 12 to 16 minutes prior to induction of anesthesia.

Comparisons of the 3 groups showed: (1) patients receiving nalbuphine and morphine had a significant reduction of minute ventilation and a significantly greater incidence of immediate side effects than did patients receiving placebo injections; (2) patients receiving morphine required no medication for pain in the early postoperative period; and (3) patients receiving nalbuphine experienced less nausea and/or vomiting postoperatively than did those in the other 2 groups.

Key Words: ANALGESICS, narcotics, morphine, nalbuphine • PREMEDICATION, narcotics






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1977 by the International Anesthesia Research Society.