JOURNAL HOME CME HOME THIS MONTH PAST ISSUES ETOC COLLECTIONS
AUTHORS REVIEWERS EDITORIAL BOARD FEEDBACK RSS HELP
A&A International Anesthesia Research Society
QUICK SEARCH:   [advanced]


     

Anesth Analg 1977; 56:813-816
© 1977 International Anesthesia Research Society
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a colleague
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by GOODING, J. M.
Right arrow Articles by CORSSEN, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by GOODING, J. M.
Right arrow Articles by CORSSEN, G.

A Physiologic Analysis of Cardiopulmonary Responses to Ketamine Anesthesia in Noncardiac Patients

JOHN M. GOODING, DO*, ALAN R. DIMICK, MD{dagger}, MEHRDAD TAVAKOLI, MD{ddagger}, and GUENTER CORSSEN, MD§

*Assistant Professor of Anesthesiology. {dagger}Associate Professor of Surgery. {ddagger}Associate Professor of Anesthesiology. §Professor and Chairman. Departments of Anesthesiology and Surgery, University of Alabama in Birmingham, Birmingham, Alabama 35294.

Abstract

In 16 adult patients, IV ketamine, 2.2 mg/kg body weight, did not produce dramatic effects on left heart function or systemic circulation. Minute O2 consumption and O2 delivery were stable. An appreciable elevation in pulmonary vascular resistance occurred which secondarily increased right heart work. Total intrapulmonary shunt initially increased; however, the effect was short lived and did not cause clinical alterations in PaO2. The authors conclude that physiologic alterations associated with ketamine are more pronounced on the pulmonary than on the systemic vascular bed, and to the right rather than to the left side of the heart.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1977 by the International Anesthesia Research Society.