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Anesth Analg 1979; 58:139-140
© 1979 International Anesthesia Research Society
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Antagonism of Neuromuscular Blockage by Theophylline

David C. Doll, MD*, and Henry Rosenberg, MD{dagger}

*Assistant Instructor in Anesthesia. Hospital of the University of Pennsylvania, Department of Anesthesia, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, Pennsylvania 19104. {dagger}Assistant Professor of Anesthesia and Pharmacology. Hospital of the University of Pennsylvania, Department of Anesthesia, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, Pennsylvania 19104.

Abstract

Theophylline has recently been reported to antagonize nondepolarizing neuromuscular block in animals.1 To our knowledge, however, there has been no report of theophylline affecting neuromuscular transmission in humans. In this report we describe diffi- culty in achieving a nondepolarizing neuromuscular block in a patient who was receiving aminophylline by constant infusion.




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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1979 by the International Anesthesia Research Society.