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Ketanserin and Guanethidine in the Treatment of Causalgia

Selly Oak Hospital, Birmingham, England.

Abstract

Reflex sympathetic dystrophies such as causalgia are notoriously difficult to manage even when treatment is started early. Treatment after the condition has been present for more than a year results in a success rate of less than 5% (1). Vasodilatation is not uncommon in the early months but the established condition invariably contains an element of vasoconstriction. Treatment is mainly directed at reducing painful transmission with local anesthetic agents and improving the circulation. We report a patient who, after having 75 guanethidine intravenous regional blocks for causalgia, was successfully treated with ketanserin.

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Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999