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Anesth Analg 1987; 66:731-734
© 1987 International Anesthesia Research Society
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Effect of Thoracic Epidural Bupivacaine on Somatosensory Evoked Potentials after Dermatomal Stimulation

Claus Lund, MD, Ole Bo Hansen, MD, Torben Mogensen, MD, and Henrik Kehlet, MD, PhD

Received from the Departments of Anesthesiology and the Surgical Gastroenterology, Hvidovre University Hospital, Copenhagen, Denmark.

Abstract

The effect of epidural bupivacaine (9 ml 0.5%) analgesia on early (< 500 msec) somatosensory evoked potentials (SEPs) with electrkal stimulation of the T-10 and L-1 dermatomes was examined in eight patients. Cortical amplitudes decreased only insignificantly after stimulation of both dermatomes, despite the presence of sensory analgesia (pin prick) from T-3.5 ± 0.4 to L-2.9 ± 0.4 (mean ± SEM). Latency of the SEP components remained unchanged and sensory threshold increased only insignificantly during blockade. We conclude that thoracic epidural analgesia with conventional doses of bupivacaine provides only a limited blockade of fast conducting afferent nerve fibers.

Key Words: ANESTHETIC TECHNIQUES—epidural; BRAIN—evoked potentials




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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1987 by the International Anesthesia Research Society.